From our perspective, this is game changing and for really the first time, we don’t have to fly blind. We have a biomarker, SEF95, which can be used to titrate individual propofol dosing in infants, children and adolescents. WOW
We routinely give fentanyl alone for neonatal cardiac surgery
I give remifentanil to my neonates - no volatile or benzos, dexmedetomidine if remi > 0.4 mcg/kg/min (rare)
I usually (but not always) use muscle relaxant (and reversal)
Local blocks always
Why do I need to give propofol to a human with no requirement for amnesia ?
What are we protecting them from ?
(I am sceptical of GABA induced brain rot but propofol is no better than the volatiles and you need an iv, environmental concern aside)
Why is a change in EEG an appropriate end point to justify a drug we would not normally expose a neonate to ?
Just asking but actually quite happy flying blind and eliminating the stress response
Mike
Dr Michael Clifford MBBS (Hons), FCICM, FANZCA, PGDipCU, GChPeriopMed
Ron
Sorry but I may be missing something
From our perspective, this is game changing and for really the first time, we don’t have to fly blind. We have a biomarker, SEF95, which can be used to titrate individual propofol dosing in infants, children and adolescents. WOW
We routinely give fentanyl alone for neonatal cardiac surgery
I give remifentanil to my neonates - no volatile or benzos, dexmedetomidine if remi > 0.4 mcg/kg/min (rare)
I usually (but not always) use muscle relaxant (and reversal)
Local blocks always
Why do I need to give propofol to a human with no requirement for amnesia ?
What are we protecting them from ?
(I am sceptical of GABA induced brain rot but propofol is no better than the volatiles and you need an iv, environmental concern aside)
Why is a change in EEG an appropriate end point to justify a drug we would not normally expose a neonate to ?
Just asking but actually quite happy flying blind and eliminating the stress response
Mike
Dr Michael Clifford MBBS (Hons), FCICM, FANZCA, PGDipCU, GChPeriopMed
Could someone comment on the clinical advantages of the EEG device highlighted over the BIS monitor?
Of the three approved pediatric EEG monitors, which one did they use?